Developing probiotics and natural enzymes that improve cattle health and digestive efficiency while eliminating methane.

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Focus: Mitigation or Adaptation

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Boosting cattle health and reducing methane emissions with probiotics and natural enzymes.

Hoofprint Biome is a start-up that is leveraging biotechnology to avert the climate crisis. We are engineering enzymes and probiotics to eliminate methane emissions from cattle while also improving nutritional quality and yield.  We believe that cattle are a key pillar of sustainable agriculture and human nutrition, and eliminating their methane emissions will enable transformative progress in the fight against climate change.We’re looking for a talented and dedicated team member who is passionate about animal, human, and planetary health. You must be motivated, comfortable with a fast-paced work environment, team oriented, and committed to the research mission. The best candidates will enjoy problem-solving, organizing, and supporting scientific innovation in many forms. Hoofprint works with a small research herd of dairy heifers housed at the NC State University campus. We work alongside both academic and industry groups pushing the boundaries of agricultural innovation.Who you are/what you bring:<ul><li>B.S. in Animal Science, Zoology, Biology or related field</li><li>Experience working with large animals</li><li>Previous laboratory or research experience is preferred</li><li>Strong problem solving skills, attention to detail, growth mindset</li><li>Commitment to collaboration and fostering a team-oriented culture</li><li>Excellent organizational and time-management skills</li><li>Curiosity, intention, tenacity, team mindset, and accountability to the mission</li><li>Access to a car</li><li>Ability to lift up to 50 lbs and perform physically active tasks (e.g., carrying equipment, standing for extended periods)</li><li>Must love cows.</li></ul>Responsibilities include:<ul><li>Animal Care: Assist in the daily care and management of research cattle, including feeding, watering, cleaning, and health monitoring</li><li>Data Collection and Entry: Collect samples (e.g. rumen fluid, gas, DNA) and record findings and measurements in a laboratory notebook</li><li>Sample Preparation and Analysis: Prepare biological samples and perform laboratory analysis. Assist Scientists with buffer preparation, DNA extraction, microbial quantification</li><li>Laboratory Maintenance: Maintain a clean and organized laboratory environment</li><li>Wearing Many Hats: We're a startup, we need to roll up our sleeves, stay flexible, and help wherever the company needs us most.</li></ul>We offer competitive salary and benefits include health, vision, dental, life insurance, and 401(k). We value diversity in thought from people with all types of experiences, ethnicities, talents, ages, and ideas, and we especially encourage candidates from minority and disadvantaged groups to apply.

Animal Science Technician

Hoofprint Biome is a venture-backed start-up that is leveraging biotechnology to avert the climate crisis. We are engineering enzymes and probiotics to eliminate methane emissions from cattle while also improving animal health and productivity. We believe that cattle are a key pillar of sustainable agriculture and human nutrition, and eliminating their methane emissions will enable transformative progress in the fight against climate change. We’re looking for a Laboratory Technician who is passionate about animal, human, and planetary health. We are looking for someone who thrives as a facilitator—someone who ensures our research team can focus on breakthrough discoveries by keeping the lab running smoothly and efficiently. The best candidates will enjoy problem-solving, organizing, and supporting scientific innovation in many forms. If you’re passionate about being the backbone of cutting-edge biotechnology, we want to hear from you. Key Responsibilities<ul><li>Perform basic molecular biology techniques, such as DNA purification, qPCR, western blotting, bacterial culture and gel electrophoresis</li><li>Prepare buffers, plates, reagents and stock solutions according to experimental protocols</li><li>Ensure all lab areas remain clean, organized, and compliant with safety standards</li><li>Sterilize lab materials using autoclaves, including glassware, equipment, and consumables</li><li>Maintain scientific equipment</li><li>Lab waste disposal, including hazardous and biological waste</li><li>Manage laboratory inventory</li><li>Assist other researchers preparing and executing experiments</li></ul> Qualifications<ul><li>Bachelor’s degree (BS) in microbiology, molecular biology, biology, chemistry, biochemistry, animal science, or a related field is preferred</li><li>Experience in a laboratory setting is preferred </li><li>Familiarity with basic lab equipment, aseptic techniques, and safety protocols is a plus</li><li>Strong attention to detail, organization, and time-management skills</li><li>Ability to lift up to 50 lbs and perform physically active tasks (e.g., carrying equipment, standing for extended periods)</li><li>A team player who thrives on facilitating smooth operations and solving problems before they escalate</li><li>Commitment to collaboration and fostering a team-oriented culture</li><li>Curiosity, intention, tenacity, and accountability to the mission </li><li>Must love cows.</li></ul> We offer competitive salary and benefits include health, vision, dental, life insurance, and 401(k). We value diversity in thought from people with all types of experiences, ethnicities, talents, ages, and ideas, and we especially encourage candidates from minority and disadvantaged groups to apply.

Laboratory Technician

Hoofprint Biome is a venture-backed start-up that is leveraging biotechnology to avert the climate crisis. We are engineering enzymes and probiotics to eliminate methane emissions from cattle while also improving animal health and productivity.  We believe that cattle are a key pillar of sustainable agriculture and human nutrition, and eliminating their methane emissions will enable transformative progress in the fight against climate change.We’re looking for a talented Principal Scientist who is passionate about animal, human, and planetary health. You must be motivated, comfortable with a fast-paced work environment, team oriented, and committed to building exceptional products. Your role relies on mentorship, scientific design, and wet-lab execution.The Principal Scientist will serve as a key leader of scientific initiatives across enzyme and strain engineering. This role requires both leadership and hands-on contributions in the lab, ensuring seamless communication, efficient experimental design, and a high quality of work. In partnership with the Chief Scientific Officer, the Principal Scientist will design and execute experiments, write and oversee protocols, and provide guidance to the team of scientists and research associates to achieve organizational objectives.Key Responsibilities<ul><li>Design and oversee execution and analysis of experiments in enzymology, microbiology, strain engineering, and protein engineering.</li><li>Develop and leverage an understanding of rumen microbial dynamics in experimental design.</li><li>Work with Scientists and RAs on detailed experimental plans and processes, including identification of appropriate controls, assay design and optimization, reagent selection, proper execution, and data analysis.</li><li>Mentor young scientists: expanding their breadth of knowledge, helping them troubleshoot experiments, and guiding them through new experimental workflows.</li><li>Present finding and project updates to internal research and executive teams</li><li>Assist in authoring technical reports for intellectual property, grant applications, and regulatory filings</li><li>Play a key role in building and fostering Hoofprint’s culture and contribute to the growth and leadership of the bioengineering team</li><li>Collaborate on various aspects of general business, lab operations, and people operations as needed. </li></ul>Qualifications<ul><li>PhD in a relevant scientific field (e.g., bioengineering, biochemistry, chemistry, biology, microbiology, chemical engineering, or a related discipline).</li><li>5+ years of relevant experience in biotech R&amp;D, at least 4 of those years spent in an industry position.</li><li>Demonstrated expertise in experimental design, protocol development, troubleshooting, and data analysis.</li><li>Thrive in team-oriented science and mentorship.</li><li>Experience with engineering biological systems (microbes, cells, proteins, DNA, and related).</li><li>Proficient in lab techniques and tools relevant to the organization’s research. These include molecular cloning, microbial fermentation and culture, protein expression, protein purification, protein characterization, protein engineering and DNA sequencing.</li><li>Excellent communication and interpersonal skills to bridge leadership and technical teams.</li><li>Proven ability to mentor and develop scientific talent.</li><li>Strong organizational and time management skills to oversee multiple projects simultaneously.</li><li>Ability to seamlessly transition across different scientific disciplines.</li><li>Commitment to collaboration and fostering a team-oriented culture.</li><li>Curiosity, intention, tenacity, and accountability to the mission. </li><li>Must love cows.</li></ul> We offer competitive salary and equity options, and benefits include health, vision, dental, life insurance, and 401(k). We value diversity in thought from people with all types of experiences, ethnicities, talents, ages, and ideas, and we especially encourage candidates from minority and disadvantaged groups to apply.

Hoofprint Biome

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